Use of Biomarkers in Early Detection and Treatment of Concussion

Authors

  • Tyler Rockwell
  • Todd Cannon

Abstract

Abstract

Background

            Athletics are an integral part of the fabric of both our country and the world. One of those dangers is the risk of sustaining a concussion secondary to minor or major trauma to the head

 

Methods

            A narrative literature review was used to investigate the use of biomarkers in detection and treatment of concussions. Specifically, whether or not the use of biomarkers allows for earlier detection and treatment of concussions and guide return to play recommendations

 

Results

            Higher levels of tau protein within 6 hours of head injury was a predictor of longer return to play times after sustaining a sport related concussion. S100B has been shown to be useful in distinguishing sport-related concussion from sport-related exertion.

 

Conclusion

            The diagnosis of concussion remains largely one of clinical presentation. In the future, ancillary testing may have the potential to aide in diagnosis, particularly once the technology and testing potential becomes widely available.

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Published

2023-05-30

Issue

Section

Medical